Collateralized Debt Positions (CDPs) are a foundational mechanism in decentralized finance, allowing users to borrow against crypto assets without selling them. By locking collateral into smart contracts, CDPs mint stablecoins or provide loans, enabling liquidity creation in a decentralized manner (Collateralized Debt Position (CDP) - Faisal Khan). This report examines the multifaceted role of CDPs in DeFi β from their economic impact and ideal use cases on various blockchains, to historical growth trends, notable successes and failures, and specific considerations for networks like TON, Solana, and Ethereum. The goal is to provide a comprehensive analysis of how CDPs have shaped DeFi and why Ethereum leads in this domain, supported by data and case studies.