The field of conservation biology stands at the precipice of a groundbreaking revolution, powered by the fusion of Web3 tools and Decentralized Science (DeSci). This formidable combination holds immense potential to transform the landscape of conservation biology, revolutionizing data transparency, collaboration, and scientific research (Fig. 1). In this essay, we will explore how the integration of Web3 tools and DeSci can contribute to conservation biology, ultimately paving the way for a more inclusive, transparent, and effective approach to preserving biodiversity\*\*.\*\*